Carcinoma of Unknown Primary in Head and Neck Region

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Head and neck squamous cell carcinoma of unknown primary: neck dissection and radiotherapy or definitive radiotherapy.

BACKGROUND Management of head and neck carcinoma from unknown primary (HNCUP) remains controversial, with neck dissection and radiotherapy (RT) or definitive RT both commonly used. The purpose of this study was to characterize HNCUP and retrospectively compare outcomes for patients treated with neck dissection + RT versus definitive RT. METHODS From 1994 to 2009, 41 patients with HNCUP underw...

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Transcervical ultrasound identifies primary tumor site of unknown primary head and neck squamous cell carcinoma.

H ead and neck squamous cell carcinomas (HNSCCs) of unknown primary site (UP) account for approximately 4% of HNSCCs. These cases have historically been subclinical tumors arising from the nasopharynx, hypopharynx, or oropharynx. In the era of human papillomavirus (HPV)–positive HNSCCs, the presence of HPV in cervical malignancy of UP has been strongly associated with oropharyngeal primary tumo...

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Positron Emission Tomography in Head and Neck Squamous Cell Carcinoma of Unknown Primary.

This article summarizes selected published studies on the use of FDG-PET and PET/CT in the workup of head and neck carcinoma of unknown primary (HNCUP). It shows that PET is a useful imaging modality in identification of the occult primary tumor and discovery of distant metastases. The results of PET often lead to a change in management in these patients. The limitations of PET in HNCUP are als...

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Head and Neck Tumors: Management of Primary Undifferentiated Pleomorphic Sarcoma

Introduction: Sarcomas account for 1% of all tumors originated in the head and neck regions in adults. They constitute a heterogeneous group of tumors of mesenchymal origin with multiple histological variants. The undifferentiated pleomorphic sarcoma (UPS) subtype is the most frequent variant with an incidence range of 2.7-38%.   Materials and Methods: This retrospective...

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Occult primary head and neck carcinoma.

Unknown primary carcinoma presenting as cervical lymph node metastasis accounts for approximately 5% of all head and neck malignancies. The typical presentation involves a middle-aged man with a painless neck mass that has been present for several months. Over 90% of these malignancies represent squamous cell carcinoma originating within Waldeyer's ring (lymphoid tissue of the nasopharynx, tons...

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ژورنال

عنوان ژورنال: Klinicka Onkologie

سال: 2018

ISSN: 0862-495X,1802-5307

DOI: 10.14735/amko2018277